21 x 76 16 these are dierent from our observed numbers

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Unformatted text preview: that the frequencies of alleles and genotypes will remain constant IF: •  1) A large number of individuals, 2) random ma/ng, 3) no natural selec/on, 4) no muta/on, and 5) no migra/on. •  In such an “ideal” popula/on the propor/on of homozygotes and heterozygotes reaches an equilibrium. •  E.g. gene A has two alleles A1 and A2. •  These occur in propor/ons p and q. •  At HWE the three genotypes will occur as: A1A1 A1A2 A2A2 p2 2pq q2 •  These propor/ons come from the probabili/es that each type of zygote will be formed from the random combina/on of any two gametes. •  For an A1A1 both gametes must be A1. If the probability of drawing an A1 allele at random is p, the probability of drawing 2 is p x p (or p2). •  Propor/on of heterozygotes is 2pq because an A1A2 heterozygote can result from an A1 egg and an A2 sperm...
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This document was uploaded on 02/15/2014 for the course BIO 286 at Purdue University-West Lafayette.

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