Lecture_03-01-21-2014

7 and a2 frequency of 03 thereforeunder hwe 49 of the

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Unformatted text preview: two alleles. •  For a diploid gene with two alleles A1 and A2 there are three possible genotypes: A1A1, A2A2, and A1A2. •  The frequency of a genotype is the number of those genotypes divided by the total number of individuals in a popula/on. An example… •  A1A1 = 48: A1A2 = 36: A2A2 = 16. Total = 100 •  Frequency A1A1 = 48/100 = 0.48, A1A2 = 36/100 = 0.36, and A2A2 = 16/100 = 0.16. •  Allele frequencies (remember DIPLOID!) for the A1 allele = 48 X 2 (A1A1) + 36 (heterozygotes) = 132. •  A2 allele = 16 X 2 + 36 = 68. •  Total number of alleles in the popula/on is 200 (100 X 2). •  Therefore frequency of A1 allele = 132/200 = 0.66. •  A2 allele = 68/200 = 0.34. •  REMEMBER ALLELE FREQUENCIES SHOULD = 1!!! Hardy- Weinberg Equilibrium •  The Hardy- Weinberg law states...
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