Lecture_03-01-21-2014

Eg populaon size migraon inbreeding dna sequencing

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: (one mutated copy and one normal copy) can func/on rela/vely normally. •  A homozygote for this gene (both copies mutated) will have severely anemia. Alleles •  Alterna/ve forms of the same gene (e.g. β- hemoglobin) are known as alleles. •  Alleles may represent neutral varia/on, or they may be expressed in the phenotype of the individual. •  Blood type in humans. •  BUT because humans (and most organisms) are diploid we inherit one allele from our mothers and one from our fathers. •  Homozygote = two copies of the same allele. •  Heterozygote = two different alleles. Gene/c markers used for studying popula/ons •  Most of the DNA in our bodies is non- coding. •  Microsatellites are tandem repeats of sequence of two, three or four nucleo/des in length. •  E.g. ACACACACACAC •  This repeat nature means there are o\en mistakes in repl...
View Full Document

Ask a homework question - tutors are online