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9.30.05 - citric(krebs acid cycle • Step 1 Getting the...

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September 30, 2005 – Cellular Respiration I. Glcolysis – 10 steps, glucose pyruvate, fermentation II. Citric Acid Cycle – NADH (intermediate storage of e- energy) NEEDS02 III. Oxidative Ohosphorylation – electron transport & chemiosmosis NEEDS O2 glycolysis Where? o Cytosol What? o Produces 2 pyruvates (6C 2C3) o Produces NADH (NAD+ reduced, energy carriers) o Substrate-level phosphorylation produces 2 molecules of ATP When? o 1 st thing Up Close: o Phosphorylate 6C to 6C-P o Phosphorylate 6C-P to P-6C-P o Lyse in half so you get: P-3C and 3C-P o Oxidize P-3C to reduce NAD+ to NADH and H+ o Get P-3C-P Subtrate Level Phosphorylization: o Enzymes create ATP from pyruvater>????????????? Look at energy chart of ppt You don’t need to memorize the 10 steps.
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Unformatted text preview: citric (krebs) acid cycle • Step 1: Getting the pyruvate in o Cleave pyruvate into CO2 and acetyl o Acetyl COA is oxidized, which reduces NADH o Acetyle COA 6C 2CO2, 2NADH, 1 ATP, 1 FADH2 o Times by two because there are two yruvates. electron transport • H+ from FADH is pumped across membrane to create a proton gradient • This proton gradient powers ATP synthaes, whih phosphorylates ADP ot make ATP. Glycolysis Krebs Oxidative Phosphorylation 2 ACOA 2 ATP 2 NADH 2 ATP 6 NADH H 2 FADH2 32-34 ATP Net Production: 36-38 ATP • Is this efficenent Yes! 7.3 kcal/col for each atp. 100% effective would be 686 kcal/mol, so this is 40% effective. Good!...
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