PSYC 211- Midterm 1 Review

Simple cells neurons whose receptive eld is organized

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Unformatted text preview: specific receptors to study their func1on 4)  Optogene1cs -   A gene1cally modified virus is used to insert a light- sensi1ve ion channel into the membrane of a par1cular neuron in the brain. Once in place, we can depolarize or hyperpolarize the neuron by applying a light of a specific wavelength to it Optogene1cs: the How To Guide 1) Take the DNA sequence that codes for light- sensi1ve ion channels from algae 2) Insert the DNA sequence into a virus 3) Insert virus into mouse brain - The virus will incorporate its DNA into select neurons in the mouse 4) Mouse now expresses light- sensi1ve ion channel. Exposing the mouse brain to light of a par1cular wavelength will ac1vate the channels Optogene1cs: the key proteins ChR2 is a sodium ion channel that opens in response to blue light; excitatory ChR- 2 Ac1on poten1als Blue light presented NpHR is a chloride ion channel that opens in response to yellow light; inhibitory NpHR Yellow light presented Gene1c methods: True/False 1)  An1sense oligonucleo1des prevent the synthesis of a protein by knocking out the gene responsible for its produc1on 2)  Dizygo1c twins share 50% gene1c material while monozygo1c twins are gene1cally iden1cal 3)  Concordance rates are used in adop1on studies to determine whether the child shares more traits with his/ her biological parents or adop1ve parents 4)  Linkage studies sequence the en1re genome across diverse popula1ons of people to determine whether differences in genomes correlate with the presence of traits 5)  Targeted muta1ons can remove a gene from birth or...
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This document was uploaded on 02/16/2014.

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