PSYC 211- Midterm 1 Review

Twins share 50 gene1c material while monozygo1c twins

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Unformatted text preview: amate and glycine –  Also ac1vated by NMDA –  PCP is an NMDA receptor antagonist –  Ac1vity is modulated by zinc and polyamines Mg2+ blocks channel at membrane poten1al –  At depolarizing poten1als Mg2+ block is relieved and NMDA receptors with glutamate bound will open GABAA receptors Ionotropic –  Selec1ve for Cl- ions –  Hyperpolarizes neuron (IPSP) GABA is the endogenous ligand -   benzodiazepines, barbituates, steroids and picrotoxin also have bindind sites Which of the following are true of Parkinson’s disease? 1)  It is characterized by an excess of glutamate in the motor cortex 2)  Degenera1on of nigrostriatal system 3)  Main neurotransmiaer involved in disease progression is serotonin 4)  L- DOPA is given to treat Parkinson’s pa1ents 5)  Parkinson’s pa1ents have trouble ini1a1ng movements Which of the following are true of Parkinson’s disease? 1)  It is characterized by an excess of glutamate in the motor cortex -   False -   The nigrostriatal pathway is a dopamine pathway involved in motor control. In Parkinson’s there is a loss of dopaminergic projec1ons in this region 2)  Caused by a degenera1on of the nigrostriatal system 3)  Main neurotransmiaer involved in disease progression is serotonin -   FALSE, the main neurotransmiaer involved in dopamine -   L- DOPA is a precursor to dopamine and it crosses the BBB -   The nigrostriatal region is involved in motor control, loss of dopaminergic projec1ons in this system are linked to motor deficits that characterize this neurological...
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