2.15.06 L52 - May 7, 2009 Lecture 52: Eukaryotic Gene...

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Unformatted text preview: May 7, 2009 Lecture 52: Eukaryotic Gene Expression Eukaryotic and Prokaryotic Differences See slide. Prokaryotes are smaller, rarely have non-coding regions, have 1 circular chromosome and 1 RNA polymerase, very rare RNA Splicing and does not need caps and tails All organisms must be able to regulate their metabolism Regulation can happen at many different levels, starting with the gene. A few features of gene regulation: o At any given time, only about 20% of our grnes are turned on. Summary of Gene Control: Level of chromosome o DNA Packing o Chromosome Puffs o Gene rearrangement o Gene amplification Transcription o Regulatory sites on oro o i.e. moters o Enhancers, etc. Post-Transcription o RNA-RNA interactions o Translational control proteins o Longevity of mrna Translation DNA Packing in euk. Chromosomes: The way that the histones pack, fold, and coil up the chromosome so that it can easily be...
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This note was uploaded on 02/11/2008 for the course BIO G 101 taught by Professor Gilbert,c. during the Fall '07 term at Cornell University (Engineering School).

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2.15.06 L52 - May 7, 2009 Lecture 52: Eukaryotic Gene...

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