Exam V, S'02 BT text

Exam V, S'02 BT text - b. Give/explain two examples of...

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BIOL 4770 Biotechnology Spring 2002 Exam V Exam Scoring Record your answers in the spaces provided. If you require more space for any of the essay 1. _______/25 questions, use the back of the page on which the question is printed. Read each question 2. _______/25 carefully. The essay questions often have multiple parts. Make sure you have answered 3. _______/30 each of them so that you will not lose points due to simple omission. The maximum points 4. _______/25 possible on this exam is 105 _______/105 Total Points 1. Transgenic animals. a. Briefly describe the conceptual strategy of making a transgenic animal. b. Give/explain two very different reasons/examples of why one might wish to create transgenic cattle or other farm animals. c. Give/explain 3 reasons why having a transgenic secrete a pharmaceutically useful protein into milk is a good strategy. 2. Transgenic mice a. What is a knockout mouse? How are they produced? What is a good reason to produce a knockout mouse?
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Unformatted text preview: b. Give/explain two examples of applications of mouse transgenics as models for research. 3. Human DNA profiling. a. What is a VNTR and what are their properties? What are/were they commonly used for (in the area of genetic analyses)? How is the procedure of RFLP carried out (describe/diagram and give results from a hypothetical VNTR locus). b. What are microsatellites/STRs and what are their properties? What are they very useful for (again in the area of genetic analyses)? 4. Gene therapy. a. What properties should be true of a genetic disease for it to be a good candidate for gene therapy (at this time)? Give 3 diseases and explain why this is true of each? b. What is ex vivo gene therapy? Give an example of such a protocol, including a possible target disease. c. What is in vivo gene therapy? Give an example of such a protocol, including a possible target disease....
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Exam V, S'02 BT text - b. Give/explain two examples of...

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