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Unformatted text preview: b. Give/explain two examples of applications of mouse transgenics as models for research. 3. Human DNA profiling. a. What is a VNTR and what are their properties? What are/were they commonly used for (in the area of genetic analyses)? How is the procedure of RFLP carried out (describe/diagram and give results from a hypothetical VNTR locus). b. What are microsatellites/STRs and what are their properties? What are they very useful for (again in the area of genetic analyses)? 4. Gene therapy. a. What properties should be true of a genetic disease for it to be a good candidate for gene therapy (at this time)? Give 3 diseases and explain why this is true of each? b. What is ex vivo gene therapy? Give an example of such a protocol, including a possible target disease. c. What is in vivo gene therapy? Give an example of such a protocol, including a possible target disease....
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- Spring '08