lecture15+more+selection

20 assume random ma0ng of genotypes ss sa aa frequency

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Unformatted text preview: e excess increases through the season Ward WaL Malaria and balancing selec0on on human hemoglobin muta0ons: Sickle cell anemia Thalassemia Homozygous individuals have lower survival Heterozygotes have lower malaria risk Sickle cell anemia: muta0on in Hb Suppose the frequency of the sickle cell allele is = 0.20. Assume random ma0ng of genotypes SS SA AA Frequency at birth 0.04 0.32 0.64 Rela0ve fitness 0.5 1 0. 5 Propor0on surviving 0.02 0.32 0.32 Frequency .02/.66=0.03 among survivors .32/.66=0.485 .32/.66=0.485 Expected H W freqs? 0.396 0.529 Sickle cell .074 Malaria resistant Malaria suscep0ble Devia0on? p = _____ ? q = _______? Suppose the frequency of the sickle cell allele is ____. Assume random ma0ng of genotypes SS Si...
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This document was uploaded on 02/19/2014.

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