lecture15+more+selection

Lecture15 more selection

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Unformatted text preview: ckle cell AA Malaria resistant AA Malaria suscep0ble Frequency at birth Rela0ve fitness Propor0on surviving Frequency among survivors Expected H W freqs? Devia0on? p = _____ ? q = _______? Suppose malaria is eliminated as a selec0ve agent. Assume random ma0ng of genotypes Ss Sickle cell Ss Malaria resistant SS Malaria suscep0ble Frequency at birth Rela0ve fitness Propor0on surviving Frequency among survivors Expected H W freqs? Devia0on? p = _____ ? q = _______? Does balancing selec0on explain other human polymorphisms? •  Why are deleterious cys0c fibrosis alleles so common? –  Cholera? Tuberculosis? Diversifying (disrup:ve) selec:on favors extreme phenotypes and increases variance Why are there so many gametophy0c self- incompa0bility alleles? Pollina0on only occurs if the pollen carries an S allele different from either maternal allele Why are there no homozygotes? Common in almonds and many other plant species Highly polymorphic- many alleles Nega0ve frequency- dependent selec0on o...
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This document was uploaded on 02/19/2014.

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