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Unformatted text preview: gnificant increase in the # of double
bonds in the membrane of the flight muscles. The birds
are inccorparting the unsaturatd fatty acids into their
flight muscles. Fat stores
Flight muscle membranes arrival A A A BIO 1140 – SLIDE 19 b b a midpoint departure www.compphys.uottawa.ca
Maillet & Weber 2006 (JEB 209, 2686-2695) The plot thickens: from endurance athletes
to couch potatoes >They also measured an activity of an enzyme called
citrate synthase (CS). This mitrochondrial enzyme is
important in generating ATP. So they found increase in
the enzyme activity, and it was correlated with the
increase of fat of the animal> this increase in body fat
through membrane signilling, might be causing the
increase of enzyme activity/synthase citrate activity. Elevated citrate synthase (CS) activity in
sandpipers Correlated with body fat Diet or other factors?
Enzyme activity (µmol min-1 g-1) Citrate synthase % body fat The plot thickens: from endurance athletes
to couch potatoes Elevated citrate synthase (CS) activity in
sandpipers Correlated with body fat Diet or other factors? Experimental test Fed quail PUFA-rich diet Found 58-90% increase in aerobic enzyme
activities Concluded that dietary lipids Regulate membrane fluidity Mimic effects of endurance training
in boosting the aerobic capacity
of muscle Fig. 6.7 BIO 1140 – SLIDE 20 Enzyme activity (µmol min-1 g-1) www.compphys.uottawa.ca
Maillet & Weber 2007 (JEB 210, 413-420) BIO 1140 – SLIDE 21 control EPA DHA EPA+DHA treatments www.compphys.uottawa.ca
Nagahuedi et al. 2009 (JEB 212, 1106-1114) > Another experiment was done where they was trying
to prove that the increase of fat causes the increase of
enzyme activity. They fed the quil bird the PUFA rich
diet and would check to see if it increased the citrate
synthase activity. And it did, the (CS) activity did
increase. Test your knowledge...
A protist (Giardia) is suddenly expelled from a warm human intestine
into cold water. Which of the following a...
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This note was uploaded on 02/19/2014 for the course BIO 1140 taught by Professor Fenwick during the Winter '07 term at University of Ottawa.
- Winter '07