Topic 2 - lipid bilayer (lec 3)

At there arrivel and after they left the bay of fundy

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Unformatted text preview: gnificant increase in the # of double bonds in the membrane of the flight muscles. The birds are inccorparting the unsaturatd fatty acids into their flight muscles. Fat stores Flight muscle membranes arrival A A A BIO 1140 – SLIDE 19 b b a midpoint departure www.compphys.uottawa.ca Maillet & Weber 2006 (JEB 209, 2686-2695) The plot thickens: from endurance athletes to couch potatoes >They also measured an activity of an enzyme called citrate synthase (CS). This mitrochondrial enzyme is important in generating ATP. So they found increase in the enzyme activity, and it was correlated with the increase of fat of the animal> this increase in body fat through membrane signilling, might be causing the increase of enzyme activity/synthase citrate activity. Elevated citrate synthase (CS) activity in sandpipers Correlated with body fat Diet or other factors? Enzyme activity (µmol min-1 g-1) Citrate synthase % body fat The plot thickens: from endurance athletes to couch potatoes Elevated citrate synthase (CS) activity in sandpipers Correlated with body fat Diet or other factors? Experimental test Fed quail PUFA-rich diet Found 58-90% increase in aerobic enzyme activities Concluded that dietary lipids Regulate membrane fluidity Mimic effects of endurance training in boosting the aerobic capacity of muscle Fig. 6.7 BIO 1140 – SLIDE 20 Enzyme activity (µmol min-1 g-1) www.compphys.uottawa.ca Maillet & Weber 2007 (JEB 210, 413-420) BIO 1140 – SLIDE 21 control EPA DHA EPA+DHA treatments www.compphys.uottawa.ca Nagahuedi et al. 2009 (JEB 212, 1106-1114) > Another experiment was done where they was trying to prove that the increase of fat causes the increase of enzyme activity. They fed the quil bird the PUFA rich diet and would check to see if it increased the citrate synthase activity. And it did, the (CS) activity did increase. Test your knowledge... A protist (Giardia) is suddenly expelled from a warm human intestine into cold water. Which of the following a...
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