Unformatted text preview: hat four ring
framework, there is a hydroxal group at one end, and that hydroxal
group is polar, and there is a hydrocarbon chain at the other end,
and it is non-polar. As a whole this molecule is quit non-polar,
except for that small hydroxal group. b/c of that it is inserted into the
membrane in a particular fashion. The hydrocarbon rings tend to be
buried into the membrane in the fatty acid chains, and the small
polar hydroxal group is oriented towards the polar head groups of
the phospholipids. Steriols show different abundences in different
groups. Prokaryotic cells lack steriols completely. Steriols are found
in only eukaryotic cells. In animal cells and some protists, the main
steriol is Cholesterol. In plants the steriol is called Phytosterols ,
and fungi have a steriol called Ergosterol. Steriols are present in
eukaryote cells, but the type of steriol that is present varies from
one group to another. This four ringed structure is quite rigided
incompariosn to fatty acid tails. b - It is difficult for hydrophilic molecules to traverse the
hydrophobic cone of the lipid bilayer Test your knowledge...
Which of the following remedies is likely to be most effective against
athlete’s foot, a fungal infection of the human foot? a. Oseltamivir, an anti-viral agent better known as tamiflu.
b. Micronazole, an inhibitor of ergosterol synthesis.
c. Penicillin, an inhibitor of peptidoglycan (bacterial) cell wall formation.
d. Sodium azide, an inhibitor of oxidative metabolism.
e. None of the above b- Micronazole, an inhibitor of ergosterol synthesis this
is b/c it is more selective where as in (d) it would kill off
the fungus but also kill of the cells in the foot Explain your answer. BIO 1140 – SLIDE 13 > The properties of the membrane. The two halves of the lipid
bilayer are not the same. We have a lipid bilayer made up of two
leaflets, the composition of each half is different. These difference
come from the way the membrane is synthesized, the different
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This note was uploaded on 02/19/2014 for the course BIO 1140 taught by Professor Fenwick during the Winter '07 term at University of Ottawa.
- Winter '07