Topic 2 - lipid bilayer (lec 3)

The four hydrocarbons are linked together in the case

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Unformatted text preview: hat four ring framework, there is a hydroxal group at one end, and that hydroxal group is polar, and there is a hydrocarbon chain at the other end, and it is non-polar. As a whole this molecule is quit non-polar, except for that small hydroxal group. b/c of that it is inserted into the membrane in a particular fashion. The hydrocarbon rings tend to be buried into the membrane in the fatty acid chains, and the small polar hydroxal group is oriented towards the polar head groups of the phospholipids. Steriols show different abundences in different groups. Prokaryotic cells lack steriols completely. Steriols are found in only eukaryotic cells. In animal cells and some protists, the main steriol is Cholesterol. In plants the steriol is called Phytosterols , and fungi have a steriol called Ergosterol. Steriols are present in eukaryote cells, but the type of steriol that is present varies from one group to another. This four ringed structure is quite rigided incompariosn to fatty acid tails. b - It is difficult for hydrophilic molecules to traverse the hydrophobic cone of the lipid bilayer Test your knowledge... Which of the following remedies is likely to be most effective against athlete’s foot, a fungal infection of the human foot? a. Oseltamivir, an anti-viral agent better known as tamiflu. b. Micronazole, an inhibitor of ergosterol synthesis. c. Penicillin, an inhibitor of peptidoglycan (bacterial) cell wall formation. d. Sodium azide, an inhibitor of oxidative metabolism. e. None of the above b- Micronazole, an inhibitor of ergosterol synthesis this is b/c it is more selective where as in (d) it would kill off the fungus but also kill of the cells in the foot Explain your answer. BIO 1140 – SLIDE 13 > The properties of the membrane. The two halves of the lipid bilayer are not the same. We have a lipid bilayer made up of two leaflets, the composition of each half is different. These difference come from the way the membrane is synthesized, the different phosphoglyce...
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This note was uploaded on 02/19/2014 for the course BIO 1140 taught by Professor Fenwick during the Winter '07 term at University of Ottawa.

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