lecture 8 outline - fig 11-28 b) The transporter...

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Lecture #8: Membranes and Transport I. Membranes A. Composition fig 11-3 1. The relative proportions of protein and lipid differ in different membranes table 11-1 2. Example functions of some membrane proteins
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3. Abundance of different lipids B. Key Points about Membrane Structure fig 11-3 again 1. Membranes are asymmetric
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2. Membranes are fluid fig 11-16
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C. Membrane Proteins 1. Integral Membrane proteins figs 11-8, 11-7, 11-9, 11-11
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2. Peripheral Membrane Proteins fig 11-6
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3. Isolating membrane proteins fig 11-4 again 4. Protein movement in the membrane fig 11-19
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II. Transport Across membranes A. Passive transport: movement down a concentration gradient 1. Simple diffusion 2. Facilitated diffusion a) What kinds of molecules require aid in transport and why?
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Unformatted text preview: fig 11-28 b) The transporter compensates for the energetic barrier c) Transporters act like enzymes d) Proposed model for GluT1 mechanism fig 11-32 B. Active Transport: Movement against a concentration gradient Requires energy input 1. Primary Active Transport (Pumps) figs 11-37 2. Secondary Active Transport: driven by cotransport with another molecule down its concentration gradient fig 11-34 C. The Electrochemical Gradient 1. The Chemical Component 2. The Electrical Component 3. Chemical + Electrical = Electrochemical D. Ion Channels 1. Ion movement results in a large change in the electrical potential across the membrane 2. Ions move down a concentration gradient 3. Differ from permeases 4. Example = Acetylcholine Receptor on nerve cells figs 12-5...
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This note was uploaded on 04/07/2008 for the course BIO 100 taught by Professor Rothwell during the Summer '08 term at University of California, Santa Cruz.

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lecture 8 outline - fig 11-28 b) The transporter...

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