2.17.06 L53 - Lecture 53 The Immune System The Body's...

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May 7, 2009 Lecture 53: The Immune System The Body’s Defense Primary : The Walls – Physical Defenses o Our skin, epithelia (in and out of body, i.e. lung ep)  Secondary : Soldiers – Cellular attacks o Macrophages, Neutrophils, NK Cells, Dendrytic Cells Tertiary : Sentinels – Immune Responses o B and T Cells Where the War is fraught: bone marrow, blood, lymph, etc… Blood Cell Types All start from bone marros Erythroid Preogrnitors o RBCs and platelets Granulocytes o Neutrophils (WBCs) o Eosophils Monoctyes Lymphocytes o NK – Natiural Killer Cells o B-Cells Plasma Bs – Humoral (think Bs=Blood Memory BS o T-Cells (cellular) Cytotoxic T-Helpers Regulatory NON-SPECIFIC [Innate] Defenses Barriers – Skin & Mucus from epithelia Cellular Responses o Phagocytosis  by neutrophils, macrophages, & NK Cells (also release cytokines,  increasing alertness of system).
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  • Summer '07
  • GILBERT,C.
  • cells, NK Cells, plasma cells, Cells Secrete Antibody

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