2.06.06 L48 - Lecture 6 DNA and Replication Watson Crick...

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
May 13, 2009 Lecture 6: DNA and Replication Watson & Crick Model Two strand running in opposite directions Produces spiral helix. Structure of DNA Composed of Deoxyribose sugar, phopate groups, 2 phosphate linkages,  5’, 3’, antiparallel Double helix Dna makes itself, and RNA, which then produces proteins.  What is the Mechanism of Replication? Watson and Crick propose a “template” model for each strand Kornberg: Learned that DNA Polymerase was necessary for test tube replication Semi-consrvation o Semi-conservation: DNA is half conserved, half new o Conservative: Entire DNA is new, parent helix is retained, and entire new daughter helix  is produced. Meselson & Stahl – Confirmed visually (using staining) that the semi-conservative model  is correct. DNA Replication: Prokaryotes Single point of origin Replication bubble is formed as are two replication forms 2 strand of dna unzip and a new strand is laid down on each string.
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern