Fed state glucose acetyl coa cholesterol fasted state

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Unformatted text preview: State Glucose Fasted State Glycerol- 3- phosphate TAG FaEy Acids FaEy Acids TAG 7 12/10/13 Muscle Tissue Ac<ve State Inac<ve State Glucose Glucose Glycogen FaEy Acids Acetyl CoA Ketone Bodies How does the liver “know” when it should store glucose as glycogen or ship out glucose/ketone bodies? Fed State Glucose Acetyl CoA cholesterol Fasted State Glycogen Glycogen Glucose TAG Acetyl CoA Ketone Bodies TAG VLDL 8 12/10/13 Glucose Glycogen Glucose-6-P 6-phosphogluconoδ−lactone Glucose-1-P Fructose-6-P fatty acid acyl CoA Fructose-2,6-bis P Fructose-1,6-bis P malonyl CoA malate oxaloacetate phosphoenolpyruvate acetyl CoA oxaloacetate pyruvate malate citrate pyruvate oxaloacetate + acyl carnitine acetyl CoA malate fumarate acyl carnitine citrate acyl CoA isocitrate succinate Epinephrine binds to β-adrenergic receptors succinyl-CoA ketoglutarate Glucagon binds to G- protein coupled receptors Mobilize energy molecules acetyl CoA Insulin binds to insulin receptors Reserve energy molecules 9 12/10/13 Glucagon A signal indica<ng the fasted state A signal to store energy 10 12/10/13 Metabolic Switches 11...
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