3 phosphate dehydrogenase o ch2oh hc ch2o oh ch2opo3

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Unformatted text preview: OPO3-2 NAD+ cytoplasmic glycerol 3-phosphate dehydrogenase O CH2OH HC CH2O OH CH2OPO3-2 HC R1 C CoASH O SCoA O R1 C CH2O OH CH2OPO3-2 C R1 O C R2 CH2OPO3 -2 HC R2 C CoASH O SCoA O O Pi CH2O HC R1 C R2 O CoASH R3 C O C CH2O C O TAG SCoA O R3 Cytoplasmic acetyl CoA used for faYy acid and cholesterol synthesis CH3 C COO- COO- CH3 NADPH NADP+ NAD+ NADH CH 2 CH2 CO CO HC OH CO2 COOCOOCOO- O SCoA ADP ATP COO- CH2 HO C COOCH2 COO- Cytosol CH3 CH3 C C O ATP COO- ADP COOCH2 C O COO- Matrix O SCoA COOCH2 HO C COOCH2 COO- Ketone body synthesis (mitochondria) Cholesterol synthesis (cytosol) Cholesterol synthesis 4C 27C 6C 6C Summary of FaYy Acid Metabolism in the Liver Co A + S glycerol-3-phosphate TAG O -O O VLDL Acyl-CoA Malonyl-CoA Acetyl CoA Acetyl CoA Acetoacetyl-CoA Acetoacetyl-CoA cholesterol HMG-CoA mevalonate Endogenous Lipid Pathway nd erol a holest sport s e' c r tran 'Rever ste erol e holest c HDL Liver Peripheral tissues VLDL Tri ac by LDL ylg lyc lipo erol h y pro tei droly n li s pas is e Fatty Acids Peripheral tissues End of Exam 4 material Nitrogen and Amino acid metabolism N2 NH4+ O H2N CH C R OH The two most important amino acids in amino acid metabolism are …. O O H2N CH C OH H2N CH C CH2 CH2 CH2 CH2 C OH O C NH2 O OH...
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