Arabidopsis the primary plant genetic model organism

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Unformatted text preview: rganism • Studies of: • mammalian development and behavior • Models for human genetic diseases. • Example: genes that control blood development of white blood cells in mice (IL-2 receptor) have homologs in humans with similar functions • Mutations in these genes result in X-linked severe combined immunodeficiency. Arabidopsis: the primary plant genetic model organism • Useful characteristics Small size (10-20 cm) Prolific reproduction Quick reproductive cycle (6 weeks) Arabidopsis: the primary plant genetic model organism • Studies of genome structure, gene regulation, development, evolution in plants • Information is applied to economically important plant species (crop species) Question Mice are the closest animal model to humans, so why don’t we use mice for all animal experiments? • Gene discovery requires the use of many animals. • Mice are expensive and slow to reproduce • Genes are discovered and characterized in invertebrate model organisms. • These genes are then studied to see how similar the function is in vertebrates. • Ethical considerations Pedigree Analysis • Pedigrees: Recognizing different patterns (Chapter 6) – Autosomal Recessive Traits – Autosomal Dominant Traits – X-Linked Recessive Traits – X-Linked Dominant Traits – Y-Linked Tr...
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This document was uploaded on 02/25/2014.

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