Yeast the simplest eukaryotic model organism

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Unformatted text preview: . coli is the most widely studied prokaryote • Fundamental discoveries in genetics, including elucidation of the genetic code • Example: many of the mechanisms used to regulate expression of genes in bacteria are also used in humans. Yeast: the simplest eukaryotic model organism • Unicellular eukaryote • Useful characteristics: • Reproduces quickly (90 minutes) • Small size • Easily grown in lab Yeast: the simplest eukaryotic model organism • Studies of basic eukaryotic cellular functions: • cell cycle, secretion, signaling, eukaryotic gene regulation, genomics • Example: DNA repair genes in yeast (e.g. RAD3) have human homologs (ATM) with the same role. • Mutations in these genes lead to cancers in humans. A basic multicellular genetic model organism • Metazoan: have a nervous system and muscles • Useful characteristics: • • • • Reproduces quickly (3 days) Large number of offspring (~200) Small size (1mm long) Easily grown in lab A basic multicellular genetic model organism • Studies of development, cell death, agi...
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