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Lecture.12.Fall.2013 - Transposable Elements Replication...

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Transposable Elements Replication October 7, 2013 Exam Post-mortem Transposable Elements • Introduction to transposons and Sleeping Beauty • Types of Transposons: - DNA transposons and retrotransposons • Mutagenic Effects • Discovery of TEs by Barbara McClintock • TE Structure in Bacteria and Eukaryotes
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Transposable Elements Replication October 7, 2013 DNA Replication (Chapter 12) Three models: Conservative, Dispersive, and Semiconservative Meselson and Stahl’s experiment to distinguish among them Modes of replication in bacteria and eukaryotes Fidelity of DNA replication
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Question 3 The pedigree of an autosomal recessive trait differs from the pedigree of an X-linked recessive trait for all of the following reasons except: a. Both parents must be carriers to have children with autosomal recessive traits, whereas a mother carrying an X-linked trait can have affected sons regardless of the genotype of the father. b. An X-linked trait is never passed from the father to his sons, whereas the father must at least carry an autosomal recessive trait for his son to get the trait. c. Pedigrees of X-linked recessive traits will have equal frequencies of affected males and females, whereas pedigrees of autosomal recessive traits will show mostly affected males. d. All of the above are correct.
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Question 3 The pedigree of an autosomal recessive trait differs from the pedigree of an X-linked recessive trait for all of the following reasons except: a. Both parents must be carriers to have children with autosomal recessive traits, whereas a mother carrying an X-linked trait can have affected sons regardless of the genotype of the father. This is true. For autosomal recessive traits, both parents must be carriers for a child to inherit the disease, while only the mother must be a carrier of an X-linked trait.
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Question 3 The pedigree of an autosomal recessive trait differs from the pedigree of an X-linked recessive trait for all of the following reasons except: b. An X-linked trait is never passed from the father to his sons, whereas the father must at least carry an autosomal recessive trait for his son to get the trait. Also true. X-linked traits can never be passed from father to son, while the father MUST be a carrier for his son to inherit an autosomal recessive trait.
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Question 3 The pedigree of an autosomal recessive trait differs from the pedigree of an X-linked recessive trait for all of the following reasons except: c. Pedigrees of X-linked recessive traits will have equal frequencies of affected males and females, whereas pedigrees of autosomal recessive traits will show mostly affected males. NOT true. X-linked recessive traits show mostly affected males, while autosomal traits (whether dominant or recessive) affect both sexes equally.
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