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Both dna and rna are present metabolically chlamydias

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Unformatted text preview: s cannot generate their own ATP via oxidation of organic molecules and rely on the energy-generating machinery of the host cell for ATP. Infect via mucosa (usually airborne or sexual transmission). OBLIGATE PARASITE CAN ONLY BE GROWIN IN MAMMALIAN CELLS. PSITTOCINE BIRDS, BIRD BECOMES INFECTED WITH C. PSITTACI, IT REPLICATES IN CELL. LONG INFECTION, AFFECTS PEOPLE WHO COME INTO REGULAR CONTACT WITH BIRDS, CLEAN BIRD CAGES C. psittaci– psitticosis C. trachomatis- conjuctivitis/urethritis/cervicitis /lymphogranuloma venerium THERE ARE 2 TYPES OF CHLAMYDIAS, ONE IS AEROSOL AND THE OTHER IS SEXUALLY TRANSMITTED SEXUALLY TRANSMITTED, FAIRLY COMMON C. trachomatis- CHLAMYDIA CAN CAUSE STILLBIRTH, NOT USUALLY LIFE THREATENING RICKETTSIAS OBLIGATE INTRACELLULAR PARASITE, HAVE DNA AND RNA, THEY HAVE COMPLETE CYTOCHROME SYSTEM AND MAKE THEIR OWN ATP, BUT OFTEN NEED THEIR OWN GROWTH FACTORS OF SOME SORT (NUCELOTIDES, ECT) T THEY CANNOT MAKE THEMSELVES. Small Gram negative bacteria that are strict intracellular parasites of warm blooded animals. The cell wall contains peptidoglycan. Both RNA and DNA are present. Some part of their life cycle is usually associated with arthropods such as fleas, ticks, or lice. They possess a complete cytochrome system and can carry out electron transport (oxidative phosphorylation), and can generate their own ATP. MOST VECTOR BORNE Typhus group: R. prowezekii-typhus fever epidemic typhus ENDEMIC TO ASIA, HIGH FEVER Spotted fever group: R. rickettsii-Rocky mounted spotted fever TICK BORNE. RECURRENT PERSISTENT FEVER DUE TO IMMUNE SYSTEM BREAKING CELLS, ECT SYMPTOM: RASH Coxiella burnetti- Q fever Life cycle of Rickettsia DO NOT HAVE CELL WALL, THEY ARE PROKARYOTIC, HAVE DNA AND RNA AND ARE PLEDOMORPHIC DUE TO NO CELL WALL. MYCOPLASMAS Do not have a cell wall. Have both DNA and RNA. and can ferment and/or respire (own cytochrome system) generating their own ATP. Most have complex nutritional requirements and serum is susually required in the medium as a source of sterols and other growth factors. Osmotically stabile despite the lack of a cell wall. Not intracellular. LIVE EXTRACELLULAR LIVE IN CLOSE ASSOCIATION WITH PLANTS AND ANIMALS, OSMOTICALLY STABLE DUE TO LACK OF CELL WALL YET CAN BE VIABLE AFTER PERIODS IF TIME Acholeplasma sp.- no cholesterol requirement, facultative DOES NOT NEED CHOLESTEROL, MOST MYCOPLASMA NEED CHOLESTEROL TO STABILIZE MEMBRANE Mycoplasma sp.- facultative, parasitic/commensal/ many pathogens M. pneumoniae- atypical pneumonia in humans M. mycoides- bovine contagious pleuopneumonia M. PNEUMONIA EASILY TREATED WITH ANTIBIOTICS, SYMPTOMS = LACK OF ENERGY AND EXUDATE IN RESPIRATORY TRACT. NOT USUALLY FATAL IN GOATS, M. MYCOIDES IS FATAL. Spiroplasma sp Ureaplasma sp. MUST HAVE INTERNAL STRUCTURE THAT ALLOWS SPIRAL SHAPE DESPITE HAVING NO CELL WALL. GENUS SPIROPLASMA, HAS SPIRAL SHAPE LIKE SPIRILLUM BUT NOT CELL WALL. CITRUS TREE ARE SUCCEPTIBLE TO SPIROPLASMA AND IS VECTOR BORNE (LEAF HOPPER). OUTBREAK TREATED BY IV DRIP ` UREAPLASMA GROW IN URINARY TRACT OF HUMANS. END OF 11/20...
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