Botulinum causes botulism via neurotoxin c

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Unformatted text preview: otulism via neurotoxin C. perfringens- several toxins (hemolytic, necrotizing, enterotoxin) C. tetani- causes tetanus SYMPTOMS: BLURRED VISION, DIFFICULTY BREATHING, THEN RESPIRATORY FAILURE Text BOTULINUM IS VERY HEAT LABILE, EASILY DENATURED BY HEAT; ALSO CANNOT LIVE IN ACIDIC ENVMT Text BOTULINAM: BOTULISM; PURE INTOXICATION, TYPICALLY IT IS A SOIL ORGANISM. ORGANISM GROWS IN CANNED PRESERVED FOODS, SPOR ARE PRODUCED, GROW IN ANAEROBIC ENVIRO THEY PRODUCE 8 DIFFERENT NEUROTOXINS ALL SPORES MUST BE KILLED IN CAN FOODS, OTHERWISE BOTULISM MIGHT BE FOUND IN CAN, MOST POWERFUL NEUROTOXIN. PRODUCE ENTEROTOXINS, CAUSES TYPICAL DIARRHEA, ECT. ALSO PRODUCE GAS GANGRENE, WOUNDS INFECTED BYT INFECTED SOIL, SPORES LIVE IN WOULD AND CAUSE GANGRENE INFECTION PRODUCES A LOT OF GAS, NECROTIZING INFECTION IS PRODUCED TETANUS: DPT VACCINATION, “TETANUS”, LIVES IN SOIL, GAS IS TRAPPED UNDERNEATH THE SKIN AND WHEN TOUCHED, TISSUE IS DESTROYED PRODUCES SPORES. SPORES BECOME EMBEDDED IN WOUND HAS NOTHING TO DO WITH RUSTY NAILS, IT COULD BE ANYTHING WITH TETANI SPORES. NEUROTOXIN IS PRODUCED, BUT IT CAUSES HYPERTENSION (MUSCLES TENSE AND CANNOT RELAX). RARE YET PREVENTABLE WITH VACCINE TYPICAL SPORE MORPHOLOGY SPORES ARE TERMINAL “TENNIS RACKET” LIKE APPEARANCE =CLOSTRIDIUM 19:02 11/18 SJ Merc 121604 Thanksgiving assignment: Please read about the following topics. Be able to describe the origin/source and the mechanism of action of each, and three properties they share in common. Text Text •polymorphonuclear neutrophil (PMN) Text Text •mucocilliatory escalator •interferon •complement (alternate pathway) GRAM POSITIVE COCCI (ONE ROD*) FALL INTO TWO GROUPS: MICROCOCCUS AND STAPHYLOCOCCUS OBLIGATE AEROBE Micrococcus sp. M. luteus: Obligate aerobe, chemoheterotroph, nonpathogenic COMMENSAL SKIN MICROBE, HANDS HAVE ALMOST PURE MICROCOCCUS POPULATION, NON PATHOGENIC; PROVIDES PROTECTION BY MAKING IT HARD FOR OTHER BACTERIA TO COMPETE ON SKIN SURFACE. ALL STAPHYLOCOCCUS ARE FACULTATIVE Staphylococcus sp. Facultative (c...
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