Ligands docking proteins are adhesins host cell has

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Unformatted text preview: CELLS? LIGANDS (DOCKING PROTEINS) ARE ADHESINS, HOST CELL HAS RECEPTORS. THESE INTERACT IN A SPECIFIC WAY. VIRUS REACTS WITH RECEPTOR SIGNAL IS SENT THAT FACILITATES FUSION OF ENVELOPE WITH CELL MEMBRANE, VIRUS GETS INTO THE CELL AND LOSES IT’S CAPSID, VIRAL GENOME INSIDE THE CELL. VARIATION: ENDOCYTOSIS: VIRUS TAKEN WITHIN A PHAGOSOME THEN FUSES WITH MEMBRANE, VIRUS GETS INTO GENOME. LOSS OF CAPSID Virus interaction with animal cells Endocytosis Virus interaction with animal cells Budding ANIMAL VIRUS IS INSIDE THE CELL AND ENSLAVES THE CELL, IT WILL MAKE VIRAL PROTEINS, CAPSIDS. GENOME IS CAPTURED WITH CAPSID IN ASSEMBLY PROCESS. WHEN IT’S TIME FOR THE VIRUS TO START LEAVING THE CELL, IT INTERACTS WITH THE CELL MEMBRANE, ADHESIN MOLECULES START TO CLUSTER AT INTERACTION POINT, VIRUS CONTINUES TO PINCH OFF AND VIRUS LEAVES THE CELL. AS IT DOES THIS, THE VIRUS CLOAKS ITSELF WITH ENVELOPE MADE OUT OF HOST CELL MEMBRANE SYNTH OF CAPSIDS, ECT PAPILLOMA INSERTED INTO PLACE WHERE IT CAN INDUCE TUMORS HIV HERPES Alteration of host cell EFFECT OR VIRUS ON HOST CELL: 19:46 TYPICALLY, LYSIS DESTROYS THE CELL IN THE PROCESS. OTHER POSSIBILITIES: EX: PAPILLOMA, BURKETT’SLYMPHOMA LYTIC INFECTION: VIRUS GOES INTO LYSOGENIC STATE AND INSERTS ITSELF INTO HOST GENOME IN A PLACE THAT INTERFERES WITH GROWTH REGULATION OF THAT CELL. IN BURKETT’S LYMPHOMA VIRUS, THE VIRUS TURNS THE CELL INTO A TUMOR CELL AND DIVIDES WITH UNINHIBITED GROWTH PERSISTENT INFECTION (HIV) THIS IS AN ENVELOPED VIRUS, IT SLOWLY BUDS OUT OF THE CELL PERIODICALLY OVER THE TIME, THE CELL WILL DIE. CELL IS NOT HEALTHY AND DOES NOT DIVIDE, BUT IS ALIVE ENOUGH TO TAKE IN NUTRIENTS REQ’D FOR THE VIRUS TO R...
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This document was uploaded on 02/25/2014 for the course MICROBIOLO 101 at San Jose State University .

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