F13 17 Viruses and Prions

The cell is enslaved persistent infection herpes

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Unformatted text preview: EPLICATE. THE CELL IS ENSLAVED PERSISTENT INFECTION (HERPES) VIRUS GETS INTO NERVE TISSUE/GANGLIONS, HANGS OUT THERE FOR A LONG TIME. EVERY ONCE IN A WHILE, STRESS/UV LIGHT CAUSES VIRUS TO COME OUT OF LYSOGENIC STATE AND PRODUCE A LESION. 22:10 Viral replication: VIRUSES MUST SYNTHESIZE THEIR GENOME AND THEY MUST SYNTHESIZE PROTEIN (ADEHSIN) IN ORDER TO MAKE PROTEIN, THEY NEED TO MAKE MRNA, IF THEY WANT TO MAKE A COPY OF THEIR GENOME, THEY NEED TO PRODUCE A STRAND OF THAT GENOME AND THEY NEED TO MAKE A COMPLEMENTARY STRAND Attachment RETROVIRUSES GO BACKWARDS, HAVE SINGLE STRANDED POSITIVE STRAND, CAN SYNTH PROTEIN IMMEDIATELY, Penetration BUT INSTEAD OF SYNTH A COMPLEMENTARY STRAND, USES REVERSE Biosynthesis: ITNA TEMPLATE TRANSCRIPTASE TO SYNTH DNA FROM R Nucleic acid replication dsDNA ssDNA dsRNA ssRNA Synthesis of protein (RNA protein) Assembly Release/Lysogeny COMPLEMENTARY STRAND T DNA FROM RNA ds RNA intermediate (template strand) DS-DNA: FOLLOW CELL LIKE PATTERN; TO MAKE PROTEIN, YOU WILL USE DNA TEMPLATE TO SYNTHESIZE MESSENGER RNA. TO MAKE GENOME, A STRAND MUST BE SYNTHESIZED AS WELL AS A COMPLEMENTARY STRAND SINGLE STRAND DNA: THERE IS NO COMPLEMENTARY STRAND, OPPOSITE STRAND MUST BE SYNTHESIZED TO USE AS COMPLEMENTARY TEMPLATE FOR SINGLE STRAND DNA. FROM INTERMEDIATE, MESSAGE CAN BE SYNTHESIZED AND PROTEINS CAN BE MADE. DBL-RNA: HAS COMPLEMENTARY STRAND, CAN SYNTH. GENOME. IT HAS A POSITIVE RNA STRAND, GENOME CONTAINS MESSAGE ALREADY. USES ONE STRAND TO SYNTH, COMPLEMENTARY STRAND AND USE IT TO MAKE PROTEIN. protein SINGLE STRAND RNA: IF POSITIVE STRAND A COMPLEMENTARY STRAND MUST BE SYNTH SO THAT IT CAN SYNTH IT’S GENO...
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