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Unformatted text preview: AD. (INFECTIOUS MATERIAL STILL ACTIVE). IF YOU WAIT LONG
ENOUGH, IT LOSES ITS ABILITY TO CAUSE DISEASE. INJECT LONG DEAD SPINAL MATTER RESULTS
IN IMMUNITY WHEN REINOCULATED WITH FRESH INFECTED BRAIN MATTER PASTEUR NEVER ISOLATED CAUSATIVE MICROBE OF RABIES; USED LOGIC TO CREATE VACCINE rabbit immune
to rabies Robert Koch (1843-1910) CONTEMPORARY OF PASTEUR; KOCH IS GERMAN; DOCTOR, MEDICAL EDUCATION
WAS PAID FOR BY PROVIDING MEDICAL SERVICE TO RURAL ENVIRONMENT • Koch's postulates: ANTHRAX 1. Identify the organism in every case of the disease and
not in healthy individuals.
2. Isolate the organism from a diseased animal and grow
the organism in pure culture away from the host animal.
3. Reintroduce the organism into a susceptible animal
and cause the characteristic disease symptoms.
4. The organism should be re-isolated from the
experimentally infected animal and have the same
characteristics as the original isolate.
OBSERVED CYLINDRICAL SHAPED ORGANISM WITH WINDOW IN MIDDLE, CONVINCED THAT THIS ORGANISM CAUSED
DISEASE, SEEN IN ALL ANTHRAX AFFECTED ANIMALS. TAKE MATERIAL FROM INFECTED ANIMAL AND INOCULATE A MOUSE,
TOOK BLOOD FROM MOUSE AND OBSERVED SAME ORGANISM EACH TIME.
COMMUNICATED FINDINGS TO ROYAL SOCIETY OF LONDON, PROVED THAT THIS ORGANISM WAS CAUSATIVE AGENT OF
ANTHRAX; LED TO KOCH'S POSTULATES Robert Koch KOCH USED METHODICAL APPROACH, PASTEUR USED LOGIC;
KOCH HAD THE IDEA THAT ORGANISM THAT GREW IN PURE CULTURE
WOULD HAVE NO OT...
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This document was uploaded on 02/25/2014 for the course MICROBIOLO 101 at San Jose State University .
- Fall '14