Lecture14-Unit5-ER&vesicles-student

15 19 clathrin coated vesicles transport selected

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Unformatted text preview: is maintained during transport and ader fusion of vesicles with target membranes. Study Guide: Vesicle Transport   Know types of coated vesicles and where they funcKon.   Be able to explain the role of adapKns, coat proteins and dynamins in vesicle budding and idenKfy which coats are acKve in ER to cis- Golgi transport (COPII); intra- Golgi and retrograde transport (COPI); PM and trans- Golgi (clathrin).   Recognize the role of SNARE proteins in vesicle fusion but don’t memorize your reading about it from the text book.   Be able to discuss how the orientaKon of membrane proteins in the lipid bilayer is maintained during transport and ader fusion of vesicles with target membranes. The endomembrane system is made up of many compartments. Cargo must be moved between them... how? EXERCISE: Can you draw the flow of traffic onto the organelle schemaKc that follows? Traffic in the Endomembrane System vesicle Once in the ER, proteins “in- transit” (also known as cargo) will follow one of the paths below depending on the signals they carry:   The secretory pathway   The lysosomal...
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