These knockout mice have high cholesterol the gene

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Unformatted text preview: acellular space. Clathrin used for vesicle forma>on in RME Adap>n = bridge between ligands and clathrin coat different adap>ns can be used to internalize different receptors An example of Receptor Mediated Endocytosis Low Density Lipoprotein (LDL) Complex that makes lipids/cholesterol water soluble and carries it in the blood A receptor makes one round trip into the cell and back every 10 min. ECB Video 15.10 Figure 13-50 & 13-51 Molecular Biology of the Cell (© Garland Science 2008) Receptor Mediated Endocytosis: e.g. LDL entry Lower pH Ligand released from receptor Figure 15- 33 Essen8al Cell Biology (© Garland Science 2010) Endocytosis A Where would M6P- containing glycoproteins enter this pathway? B C D Clicker Q16.5 Receptor- mediated endocytosis & lysosomal pathway from TGN Recycling of cell su...
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This document was uploaded on 02/26/2014 for the course BIOL 200 at UBC.

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