Do they form hydrophobic interface with each other

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: her side hydrophilic (and face aqueous environment, outside) polar SC facing water nonpolar SC facing inside polar SC facing water amphipathic α ­helix nonpolar SC facing inside amphipathic β ­sheet (strand) Loca/ons of hydrophobic and hydrophilic side chains h^p:// Could the sequence Ile ­Lys ­Val ­Glu ­Phe ­Ser (IKVEFS) form an amphipathic β ­strand? •  Two sequences: -  LAQVEKE -  LYALRKK •  Can they form amphipathic α ­helices? •  Do they form hydrophobic interface with each other? •  helical wheels: projec/ons down helix axes •  Interac/ons between R groups 3 ­4 residues apart (same side of helix) polar side polar side nonpolar interface 2....
View Full Document

This test prep was uploaded on 02/25/2014 for the course BIOC 462A taught by Professor Ziegler,baldwin during the Spring '08 term at University of Arizona- Tucson.

Ask a homework question - tutors are online