L10_ts1_2013_462a

Residues are packed beer in protein than with water

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: ac/ons contribute li^le? H ­bonds •  all poten/al donors and acceptors will form H ­bonds in the na/ve or denatured states •  denatured state – with water •  na/ve state – specific H ­bonds e.g. α ­helices and β ­sheets Ionic interac)ons •  forma/on of salt bridges within the protein involves desolva/on of the ion (unfavorable) followed by electrosta/c interac/ons between oppositely charged ions within the protein (favorable) Result: net enthalpy difference from H ­bonds and ionic interac/ons is small, but the forma/on o...
View Full Document

Ask a homework question - tutors are online