L32_carb2_462A_2013

Proteins certain hormones interferons many cell

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: ecogni5on by other proteins Facilitate protein targeHng (localizaHon) within a cell Influence protein folding Influence protein stability •  Cell ­cell recogniHon, signalling, adhesion –  Lec5ns are proteins that bind with high affinity and specificity to the carbohydrates in glycoconjugates such as glycoproteins –  Ofen appear on the surfaces of cells •  Many proteins secreted by eukaryoHc cells are glycoproteins –  anHbodies, milk proteins, certain hormones, interferons, many cell surface receptors Specificity of glycoprotein recogni5on Avian influenza virus cannot bind to receptors on human cells with the “human” glycan, but binds to avian cell receptors with the “avian” glycan. Example: P ­selec5n A cell surface lec5n that recognizes and binds specific glycoproteins on the cell surface of T ­ lymphocytes. Targets lymphocytes to site of infecHon. Lec5n (mannose ­6 ­ phosphate receptor) recogniHon of mannose ­6 ­phosphate....
View Full Document

Ask a homework question - tutors are online