Obligateintracellularparasites

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Unformatted text preview: Video 2 19 20 adsorption 21 penetration 22 Release by budding 23 Cytopathic effects­ virus­induced damage to cells 1. 2. 3. 4. 5. 6. 7. changes in size & shape cytoplasmic inclusion bodies nuclear inclusion bodies cells fuse to form multinucleated cells cell lysis alter DNA transform cells into cancerous cells 24 Cytopathic changes in cells 25 How do we grow viruses? Obligate intracellular parasites require appropriate cells to replicate. Growing animal viruses 1. live animals 2. bird embryos – chicken, duck; intact, self­ supporting unit, sterile, self­nourished 3. cell culture 27 28 29 Other noncellular infectious agents 1. prions ­ misfolded proteins, contain no nucleic acid – cause spongiform encephalopathies – holes in the brain – common in animals • scrapie in sheep & g...
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This document was uploaded on 02/25/2014.

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