chapter_7 - Definition of Frequently Used Terms Chapter 7...

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1 1 Chapter 7 Control of Microorganisms by Physical and Chemical Agents 2 Definition of Frequently Used Terms sterilization destruction or removal of all viable organisms disinfection killing, inhibition, or removal of pathogenic organisms disinfectants agents, usually chemical, used for disinfection usually used on inanimate objects 3 More definitions… sanitization reduction of microbial population to levels deemed safe (based on public health standards) antisepsis prevention of infection of living tissue by microorganisms antiseptics chemical agents that kill or inhibit growth of microorganisms when applied to tissue 4 Antimicrobial agents agents that kill microorganisms or inhibit their growth -cidal agents kill -static agents inhibit growth
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2 5 -cidal agents -cide suffix indicating that agent kills germicide kills pathogens and many nonpathogens but not necessarily endospores include bactericides, fungicides, algicides, and viricides 6 -static agents -static suffix indicating that agent inhibits growth include bacteriostatic and fungistatic 7 The Pattern of Microbial Death microorganisms are not killed instantly population death usually occurs exponentially microorganisms are considered to be dead when they are unable to reproduce in conditions that normally support their reproduction 8
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3 9 Conditions Influencing the Effectiveness of Antimicrobial Agent Activity population size larger populations take longer to kill than smaller populations population composition microorganisms differ markedly in their sensitivity to antimicrobial agents 10 More conditions… concentration or intensity of an antimicrobial agent usually higher concentrations or intensities kill more rapidly relationship is not linear duration of exposure
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