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Unformatted text preview: 1 1 Chapter 10 Metabolism: The Use of Energy in Biosynthesis 2 Anabolism synthesis of complex molecules and cellular structures turnover continual degradation and resynthesis of cellular constituents rate of biosynthesis approximately balanced by rate of catabolism requires much energy Figure 10.1 3 4 Principles Governing Biosynthesis macromolecules are synthesized from limited number of simple structural units (monomers) saves genetic storage capacity, biosynthetic raw material, and energy many enzymes used for both catabolism and anabolism saves materials and energy 2 5 More principles catabolic and anabolic pathways are not identical, despite sharing many enzymes permits independent regulation Figure 10.2 6 More principles breakdown of ATP coupled to certain reactions in biosynthetic pathways drives the biosynthetic reaction to completion in eucaryotes, anabolic and catabolic reactions located in separate compartments allows pathways to operate simultaneously but independently 7 More principles catabolic and anabolic pathways use different cofactors catabolism produces NADH NADPH used as electron donor for anabolism large assemblies (e.g., ribosomes) form spontaneously from macromolecules by self-assembly...
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- Spring '07
- Dr. D. W. Smith