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chapter_31 - Pathogenicity Chapter 31 Normal Microbiota and...

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1 1 Chapter 31 Normal Microbiota and Nonspecific Host Resistance 2 Pathogenicity ability to produce pathological change or disease pathogen any disease-producing microorganism 3 Normal Microbiota of the Human Body normal microbiota microbes regularly found at an anatomical site 4 Reasons to study normal human microbiota to gain insight into possible infections resulting from injury to understand causes and consequences of overgrowth of microbes normally absent from a body site to increase awareness of role played by indigenous microbe in stimulating immune response
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2 5 Distribution of Normal Microbiota ectosymbiosis one organism remains outside of the other endosymbiosis one organism is present within the other 6 Skin has both resident microbiota and transient microbiota mechanically strong barrier keratin intractable to microbial attack most areas subject to periodic drying slightly acidic salty inhibitory substances (e.g., lysozyme,
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