457 what are the expected genotype frequencies under

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Unformatted text preview: Aa = H freq of aa = Q book: P+H+Q=1 p = P+H/2 q = Q+H/2 p+q=1 generally: p2 + 2pq + q2 = 1 p+q=1 with popula,on data •  next week we will talk about ways of geTng molecular marker data from popula,ons •  here, we will use some made- up data •  #AA = 121 •  #Aa = 211 •  #aa = 85 •  what are p and q? •  is this popula,on at HW equilibrium for this locus? •  what is your intui-on? #AA = 121 #Aa = 211 #Aa = 85 total # inds=417 p =(#AA+#Aa/2)/total = (121+211/2)/417 = 0.543 q =(aa+#Aa/2)/total =(85+211/2)/417 = 0.457 What are the expected genotype frequencies under H-W? freq AA = p2 = (0.543)2 = 0.294 freq aa = q2 = (0.457)2 = 0.209 freq Aa = 2pq = 2(.543)(.457) = .496 What are the expe...
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