BIOC2101 Hormonal Control(1)

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Unformatted text preview: SUE 5 20/05/13 Signal Termination •  Gα subunit hydrolyses GTP to GDP slowly, thereby resetting after a number of seconds/ minutes. •  The Gα subunit can then reassociate to form the inactive heterotrimeric G protein structure. Signal Termination β-Adrenergic Receptor •  The receptor also requires resetting to prevent continual G protein activation. •  Hormone dissociation can occur. •  The hormone-receptor complex can be deactivated by phosphorylation of serine and threonine residues in the C-terminus. The Adrenal Gland Adrenaline Signal transduc;on leads to the ac;va;on of glycogen phosphorylase and the inhibi;on of glycogen synthase. Adrenaline/epinephrine...
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This document was uploaded on 02/27/2014 for the course BIOC 2201 at University of New South Wales.

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