Phys A L4

Phys A L4 - 10/15/2007 Physical Anthropology: Lecture 4...

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10/15/2007 Physical Anthropology: Lecture 4 (Chapter 3) I. Modern Synthesis A. Population Genetics: Branch of biology dealing with processes that change the genetic composition of the population through time 1. How Mendel’s genetics solves Darwin’s difficulties 2. What happens genes in populations that are undergoing natural selection B. PKU: Genetically inherited disease in humans 1. Individuals who are homozygous for PKU alleles are missing a crucial enzyme that allows them to metabolize the aa phenylalanines 2. If untreated phenylalanines builds up and can lead to mental retardation 3. Treatment is available—a low phenylalanine diet—develop normally and lead a normal life C. Evolutionary Control of the Distribution of PKU 1. Characterizes the distribution of the harmful allele a) Genotypic Frequency: A fraction of the population that carries the genotype, independent of population size b) The goal of the evolutionary theory is to determine how genotypic frequency changes through time
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This note was uploaded on 04/08/2008 for the course ANTH 5 taught by Professor Gaulin during the Fall '07 term at UCSB.

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Phys A L4 - 10/15/2007 Physical Anthropology: Lecture 4...

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