BCHE 395-3 2013 pH Buffers Titrations

2 mm what is the concentrayon of hco3 and co2 pk for

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Unformatted text preview: se of death! (and tests!) •  Small change in organism’s pH can be bad •  Physiological pH ~7.4 DescripYon of Buffer AcYon 1.  The pK of a buffer is the point at which the [conj. acid] = [conj. base] 2.  When all conjugate acid has been Ytrated the pH rises rapidly 3.  The best buffering capacity lies ~ +/- 0.7 pH units on either side of the pK and are useful only within 1 pH unit of the pK 4.  Buffer acYon is exhibited by a mixture of a weak acid and the salt of the acid OR of a weak base and the salt of the base 5.  Buffer acYon is due to a “reservoir” of free base and undissociated protons that can absorb or supply H+ Buffer Systems and Weak Acids •  Weak acids ionize to a limited extent •  HA ⇔ H+ + A- •  pH of buffer soluYon is independent of concentraYon, and essenYally based on raGo of conjugate base to conjugate acid •  1.) B...
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