BCHE 395-5 2014 Peptides and Proteins

pep0de bonds 1st 2nd carboxyl hydrolysis

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: of water molecule (dehydra0on) •  α- Carboxyl group 1st amino acid to α- Amino group 2nd amino acid (Polarity or “sidedness”) •  Chain can be lengthened by the addi0on of more residues 4 Modified figure!! Pep0de Bonds (1st) (2nd) - α- carboxyl hydrolysis + α- amino H condensa0on Dipep9de, tripep0de…oligopep0de, Polypep0de! 5 Backbone? N- C- C- N- C- C- N- C… Like a waltz 1- 2- 3… Pep0des and Proteins •  Pep0des are always wriWen and named lee to right from N- terminus to C- terminus •  SGYAL AA1 AA2 AA3 AA5 AA4 6 A pep0de bond is an amide bond formed by the condensa0on of 2 amino acids Amino- or N- terminus Carboxy- or C- terminus 7 Three ways to Write a Name 1. AYDG, a tetrapep0de Aspartate à༎ aspartyl Asparagine à༎ asparaginyl Glutamate à༎ glutamyl Glutamine à༎ glutaminyl 2. 3. alanyl-tyrosyl-a...
View Full Document

This document was uploaded on 03/02/2014 for the course BIOCHEMIST 395 at NMSU.

Ask a homework question - tutors are online