BCHE 395-6 2013 Protein Motifs and Sequencing

3 p 97 start protein sequencing 1953 frederick sanger

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Unformatted text preview: ow does it interact with other macromolecules? •  How is it related to other proteins? •  Where is it localized within the cell? •  What are its physico- chemical proper1es? 14 Importance of Amino Acid Sequence Chapt. 3, pp. 104- 105 Segel pp. 96- 98 •  Determines 3- D structure •  Reveals some structural and [email protected] [email protected] between proteins •  [email protected] [email protected] •  Provides a par1al molecular defini1on of some gene1c diseases 15 Consensus Sequences and Logos Box 3- 2 •  Consensus Sequence: comparison across proteins of primary amino acid sequence –  Proteins that have a high sequence similarity are (probably) [email protected] related –  Conserved [email protected] domains •  Reflects the most common amino acids at each posi1on ATP- binding P- loop Ca2+- binding EF hand 16 Sequence Logo: Colors denote characteris...
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This note was uploaded on 03/02/2014 for the course BIOCHEMIST 395 taught by Professor Potenza during the Spring '14 term at NMSU.

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