BCHE 395-11 2013 Enzymes Intro

trivial names ex hexokinase iec nameatp glucose

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Unformatted text preview: DP+ 11 Enzymes: Nomenclature www.chem.qmul.ac.uk/iubmb/enzyme •  Two systems: •  1.) InternaKonal Enzyme Commission (I.E.C.) System (1958) –  Chemically informaKve and based on chemical reacKons –  Classifies enzymes into 6 major categories, sub, and sub- sub classes –  Used in journal, abstract, indexes, official stuff –  PrePy much never used in text books/class 12 Yes, you will have to idenKfy reacKon classes of the individual enzymes we deal with in class! •  •  •  •  •  •  •  Enzymes: Nomenclature Classes: (1) oxido- reductases: oxidaKon and reducKon (2) transferases: transfer of funcKonal groups (3) hydrolases: hydrolysis reacKons (e.g. trypsin) (4) lyases: addiKons/subtracKons to double bonds (5) isomerases: isomerizaKon reacKons (6) ligases: formaKon of bonds with cleavage of ATP 13 Enzymes: Nomenclature •  2.) Trivial Names –  Ex. Hexokinase –  I.E.C. nameà༎ATP: glucose- phosphotransferase [2.7.1.1] –  2. transferase; 7. sub class phosphotransferase; 1. hydroxyl group as an acceptor; 1. D- glucose as the phosphoryl- group acceptor •  Recognize that it is an enzymes by the “- ase” suffix 1...
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This note was uploaded on 03/02/2014 for the course BIOCHEMIST 395 taught by Professor Potenza during the Spring '14 term at NMSU.

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