{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

BCHE 395-11 2013 Enzymes Intro

The equilibrium constant for the reackon linked to g

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: heory E + S ⇌ [ES ⇌ES⧧⇌EP] ⇌ E + P •  Chemical reacKons DO NOT occur instantaneously •  Always intermediates before final product formed •  Intermediates are highly energe8c (when compared to substrate and products) •  Can think of them with “parKally broken” (stretched) bonds and “parKally formed” new bonds, exisKng in the same intermediate •  Can plot a reacKon TransiKon state ethanol Ethyl- bromide commons.wikimedia.org/wiki/File:TransiKon_State.png 19 TransiKon State •  This symbol denotes transiKon state: ⧧ •  Remember: TransiKon state structure of a substrate is not that of either the substrate (S) or product (P) •  It is at a higher energy and energe8cally unstable with respect to both S and P 20 Is the reacKon spontaneous or nonspontaneous? Is the reacKon exergonic or endergonic? Does the equilibrium favor S or P? What about the REVERSE reacKon? What about rate? ReacKon Coordinate Diagram •  Magnitude of the ac8va8on energy represents the energy barrier and determines the rate of the reacKon •  ΔG’°= standard free energy change for the ground state of S and P does NOT change...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern