11-18-13 signaling questions (1)

How is arrestin involved in feedback

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Unformatted text preview: ory subunit in the presence of DAG/Ca2+, and why? What are the main amino acids that can be phosphorylated by kinases? Which of these can be phosphorylated by PKA? What are some effects that phosphorylation can have on protein structure and function? In the context of GPCR signaling, how do PKA and PKC get activated, and how does this result in feedback inhibition/adaptation/attenuation of GPCR activity? How is arrestin involved in feedback inhibition/adaptation/attenuation of GPCR activity? How does it get targete...
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