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11-18-13 signaling questions (1)

Where is the function of the ps domain in the

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Unformatted text preview: gh in the cytoplasm? What about in the ER? What about extracellularly? How are these concentrations maintained? Describe the domain structure of PKC: what roles does each domain have? In the absence of DAG/Ca2+ what is the relationship between the PKA regulatory and catalytic domains? Where is the function of the PS domain in the regulatory domain? How does this prevent PKC activation? What happens to the regulat...
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