Describe the structural features that account for the selectivity of the K

Describe the structural features that account for the selectivity of the K

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Describe the structural features that account for the selectivity of the K+ channel protein for potassium and not sodium. The selectivity begins with the primary structure of the potassium channel. All potassium channels include a region of almost identical amino acids in part of their sequence. For
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: example, according to figure 1, the pore helix includes the sequence TVGYG with just four amino acid exceptions in fourteen potassium channel sequences. The last two sequences however do not display potassium selectivity, and both appear to lack the YG on the end of the identical amino acid region....
View Full Document

This note was uploaded on 02/11/2008 for the course CHEM 2080 taught by Professor Davis,f during the Spring '07 term at Cornell.

Ask a homework question - tutors are online