Calculate g when the creatine kinase reaction occurs

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Unformatted text preview: les are stable in the presence of H2O or O2. Explain why. 2 15. Phosphocreatine can be used as a phosphoryl donor for the synthesis of ATP in a reaction catalyzed by creatine kinase. Refer to table 15.1 in the text for the free energies of hydrolysis for ATP and creatine phosphate. Write the equation for the reaction catalyzed by creatine kinase. Calculate the value of the ∆G˚’ for the reaction. Is the reaction energetically favorable? What effect does the enzyme have on the value of ∆G˚’ for the reaction? The concentration of a number of compounds in human muscle are as follows: [ATP]=10mM, [ADP]=1mM, [Pi]=10mM, [phosphocreatine]=30mM, [creatine]=1mM. Calculate ∆G when the creatine kinase reaction occurs in human muscle at 25°C. 16. In a typical cell, the concentrations of pyridine nucleotides and flavins are relatively low compared to the number of substrate molecules that must be oxidized. How is this possible, and what does it suggest about the rates of oxidation and reduction of these electron carriers? 17. Chemotrophs (us) derive free energy from the oxidation of fuel molecules, such as glucose and fatty acids. Which compound, glucose or a saturated fatty acid containing 18 carbons, would yield more free energy per carbon atom when subjected to oxidation in the cell? Why? 18. Under aerobic conditions, what happens to the pyruvate generated by glycolysis? Under anaerobic conditions? Why do anaerobic organisms want to do this? 19. Since there are 2 energy ­producing steps and 2 energy ­requiring steps, each burning or producing an ATP, why is there a net gain of 2 ATP's? 20. Calculate what percentage of the starting concentration of fructose 1,6...
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