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1998 32 nitric oxide synthase the switch is ca calcium

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Unformatted text preview: ) Neuronal Nitric Oxide Synthase, nNOS •  regulator of skeletal muscle contrac8lity, owing to the associa8on of nNOS with the dystrophin ­ associated glycoprotein complex •  pathology is Duchene muscular dystrophy •  29 exons spans a region greater than 240 kb Epithelial Nitric Oxide Synthase, eNOS e Kyoto study shows Glu298Asp muta8on correlated with hypertension (Hypertension. 1998; 32) Nitric Oxide Synthase, the switch is Ca++ •  calcium regula.on –  Both nNOS and eNOS are cons8tu8ve...
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