Lecture_10_2013_Integration(1)

23 formerly threshold total synapcc current ik ina

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Unformatted text preview: 2008 1 2/16/13 Adding inhibitory inputs blocks the response to the excitatory input. The effect is mainly due to the inhibitory conductance change (inhibitory shunCng). Subthreshold EPSPs only (threshold is now GEx=0.23) formerly threshold total synapCc current! IK! INa! IIn! IEx! Although the inhibitory conductance is large, the current (and IPSP) is small, because (V- EIn) is small GEx = 0.05 0.13 0.17 0.19 0.21 (plus GIn = 0.2) Excit. here What is the effect of relaCve placement of synapses on the dendrites? Because cells are not electrically compact, the relaCve placement of synapses on dendrites ma_ers. or Why inhibitory synapses cluster near the soma. EE F = ––– EI at 2 at S EE EI at 1 at 3, 4, 5 Koch et al., 1983 2 2/16/13 Bec...
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