Lecture_10_2013_Integration(1)

Below are calcium signals from spines in auditory

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: ligible cable effect. CalculaCons show that the current injected into a dendrite by a synapse on a spine head is about the same as if the synapse were directly on the dendrite. Vspine Vd 5 2/16/13 NMDA The calcium signal in spines is an essenCal message for postsynapCc plasCcity, discussed in a subsequent lecture. Confining Ca to a single spine makes the changes produced by that Ca specific to the synapse on the same spine. AMPA Ca ATPase VGCaCh Ca mGluR Ca- B IP 3 ER Dendrite spine In fact, spines are calcium traps, the length constant for calcium diffusion in dendrites is very short, approximately the length of a spine neck. a. shows 2- photon...
View Full Document

This document was uploaded on 02/28/2014.

Ask a homework question - tutors are online