Vspine vd 5 21613 nmda the calcium signal in spines

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: ranches. These produce amplified EPSPs in the soma. SomaCc EPSPS (data) DendriCc NMDA spikes and somaCc EPSPs in a model. ProperCes of NMDA channels: leh - gaCng Cme following neurotransmi_er release; right – current- voltage plot in 1 and 2 mM Mg++. Note the acceleraCng inward current, as in a sodium or calcium channel. Rhodes 2006 4 2/16/13 morphology of dendrites and spines every spine (gray) has a synapCc terminal (colored) EM level pictures of spines, showing synapCc densiCes uncaging glutamate acCvates the soma only when it is done near a spine Soma depolarizaCon Spruston 2008 What is the effect of spines on input/output processing in a neuron? Spines do not have a significant electrical effect: the worst- case electrotonic length (L) of the spine neck is about 0.02, so there is neg...
View Full Document

This document was uploaded on 02/28/2014.

Ask a homework question - tutors are online